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Workshop speakers in the spotlight: Barbara Howard and Eric Bruckert

Focus on... EAS 2012 Milan

Workshop: Sunday, May 27, 2012, 11:00–12:30

PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE
How should a healthy diet look like - any need for supplements?

 

Dr. Barbara V Howard, USA

Barbara Howard is Senior Scientist and former President of MedStar Research Institute. She is the current chair of the American Heart Association Council on Nutrition, Physical Activity, and Metabolism. The focus of her research is investigation of risk factors for cardiovascular disease (CVD), with special interest in diabetes, lipids, and the effects of diabetes on CVD in women. Dr Howard chairs the Steering Committee for the Strong Heart Study, and is also involved in the Women's Health Initiative, GOCADAN, a study of the genetics of CVD in Alaskan Eskimos, and the SANDS study, an evaluation of the effects of aggressive reduction in low-density lipoprotein (LDL) cholesterol and blood pressure on CVD in people with diabetes.

Prof. Eric Bruckert, France

Eric Bruckert is Professor of Medicine, Department of Endocrinology and Metabolism; Head, Endocrinology and Cardiovascular Disease Prevention, Hôpital Pitié-Salpêtrière, Paris, France. He is a Founding member of ARCOL (French Committee for the Co-ordination of research in Atherosclerosis and Cholesterol). His research is focused on the prevention and management of dyslipidaemia, obesity and CVD.

 

Lifestyle underpins modern preventive cardiology, as recognised by the recently published EAS/European Society of Cardiology joint guidelines for management of dyslipidaemia. In particular, diet is a key determinant of cardiovascular risk, supported by observational data showing that a "healthy" Mediterranean-type diet favourably influences dyslipidaemia and is associated with reduced risk of CVD and type 2 diabetes. Additionally, monounsaturated fatty acids intake has been shown to modulate the expression of key genes associated with the development of atherosclerosis.

Escalating rates of obesity and cardiometabolic disease, driven by adoption of a sedentary lifestyle and consumption of energy-dense diets has led to renewed consideration of approaches that combine nutritional and pharmacotherapeutic interventions to reduce cardiovascular risk. In patients with overt CVD, there is increasing evidence of positive cardiovascular effects associated with supplementation with dietary fibers, cholesterol-lowering natural agents such as plant sterols (i.e. phytosterols), olive oil and omega-3 PUFAs.

Whether such functional foods should be integral components of a ‘healthy diet’ is the focus of discussions at this workshop.

Key references

Horn LV, Tian L, Neuhouser ML, Howard BV, Eaton CB, Snetselaar L, Matthan NR, Lichtenstein AH. Dietary patterns are associated with disease risk among participants in the Women's Health Initiative Observational Study. J Nutr 2012;142:284-91.

Margolis KL, Wei F, de Boer IH, Howard BV, Liu S, Manson JE et al; Women’s Health Initiative Investigators. A diet high in low-fat dairy products lowers diabetes risk in postmenopausal women. J Nutr 2011;141:1969-74.

Genser B, Silbernagel G, De Backer G, Bruckert E, Carmena R, Chapman MJ et al. Plant sterols and cardiovascular disease: a systematic review and meta-analysis. Eur Heart J 2012;33:444-51.

Bruckert E, Rosenbaum D. Lowering LDL-cholesterol through diet: potential role in the statin era. Curr Opin Lipidol 2011;22:43-8.

Forrás: The European Atherosclerosis Society website

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